Farmed shrimp (usually in high density aquaculture) are especially vulnerable to disease. Antibiotics have historically been used to control disease outbreaks in shrimp aquaculture. But the combination of microbial resistance and consumer resistance to the use of antibiotics creates a need for alternatives for disease control in shrimp farming operations. The use of specialized, preselected microbial additives to enhance productivity and quality in shrimp aquaculture is becoming increasingly common. This study explains the use of probiotics and specialized microbial products in aquaculture.